Riboflavin sodium phosphate
130-40-5
C17H20N4NaO9P
478.33
Riboflavin 5′-monophosphate sodium salt, Riboflavin Sodium phosphate
USP/BP/EP
| Product | Specifications |
|---|---|
| Riboflavin sodium phosphate | USP |
| Riboflavin sodium phosphate | BP |
| Riboflavin sodium phosphate | EP |
The most reputable manufacturers worldwide
GUANGJI / China
BASF / German
DSM / Nederland
HEGNO / China
ENBEI / China
Riboflavin sodium phosphate Properties
- Melting point:
- >300°C
- FEMA
- 2976
- refractive index
- 41 ° (C=1.5, 5mol/L HCl)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble50mg/mL, clear, orange
- Water Solubility
- almost transparency
- Merck
- 14,8201
- Stability:
- Stable. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. Protect from light, air and moisture.
- EPA Substance Registry System
- Riboflavin 5'-(dihydrogen phosphate),monosodium salt(130-40-5)
SAFETY
| Hazard Codes | Xi | ||
|---|---|---|---|
| Risk Statements | 36/38 | ||
| Safety Statements | 22-24/25-37/39-26 | ||
| WGK Germany | 3 | ||
| F | 3-8-10 |
Description
Riboflavin-5-phosphate sodium (sodium FMN) consist mainly monosodium salt of Riboflavin 5-phophate (FMN),the 5-monophosphate ester of riboflavin. Riboflavin-5-phosphate sodium is produced by direct reaction of riboflavin with a phosphorylating agent such as phosphorous oxychloride in an organic solvent.
Riboflavin 5-phophate (FMN) is essential as a coenzyme in various enzymic reactions in the body and is therefore used in the form of its salts, especially in the form of sodium FMN, as additive to drugs and human and animal food. Sodium FMN is also used as starting material for flavin adenine dinucleotide which is employed for treating vitamin B2 deficiency. It is used as a yellow food color additive (E106). Riboflavin 5-phosphate sodium is fairly stable in air but is hygroscopic and sensitive to heat and light. The product may be stored for 33 months from the date of manufacture in the unopened original container and at a temperature below 15 °C.
References
[1] https://en.wikipedia.org/wiki/Flavin_mononucleotide
[2] Scientific Opinion on the re-evaluation of riboflavin (E101(i)) and riboflavin-5'-phosphate sodium (E 101(ii)) as food additives, EFSA Journal 2013
[3] Patent US 5095115A: Preparation of riboflavin 5'-phosphate (fmn) and its sodium salt in a lactone
Chemical Properties
Uses
One of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).
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